CSB2: Council for Systems Biology in Boston

Systems Biology of Human Disease 2009

June 18-19, 2009 in Boston, MA

SBHD 2009 included over 200 participants, 53 poster presenters, and 17 talks. SBHD 2010 is scheduled for June 16-18 at Harvard Medical School. Details of the 2010 conference and registration will be available via this site – check back in January 2010 for details.

Systems Biology of Human Disease 2009 is a two-day conference featuring sessions on cellular responses and decisions, signaling pathways and systems pharmacology, and new genomic- and proteomic-based approaches to understanding disease. In addition to the main sessions, SBHD will include a poster session (on June 18) and additional talks selected from submitted poster abstracts.

Location

The Joseph B. Martin Conference Center
Harvard Medical School
77 Avenue Louis Pasteur
Boston, MA 02115

Pricing and Deadlines

Registration Type		Early	Regular	Late
Deadline		April 15	May 15*	June 19
Cost	Student	$60	$90	$90
Cost	Non-Student	$80	$120	$160

* Poster abstracts deadline is extended to May 27!

Walk-up registration will be available on the day of the conference at the Late registation cost.

Nominated Speakers & Poster Prizes

We particularly invite the submission of poster abstracts. Maximum poster size is 48 inches by 48 inches. The Program Committee will review all abstracts and nominate the top two submissions for full-length talks. Several more posters will be selected for “lightning talks” – these are short talks (less than 5 minutes, 1 slide) designed to preview the poster presentation.

Schedule

Thursday, June 18, 2009

7:45am – 8:15am	Continental Breakfast & Registration
8:15am – 8:30am	Peter Sorger, Harvard Medical School Welcome & Opening Remarks
Session One: Cell Signaling and Disease
8:30am – 9:10am	Douglas Lauffenburger, Massachusetts Institute of Technology Quantitative Systems Analysis of Tumor Cell Migration
9:10am – 9:50am	Richard Bond, University of Houston Beta- Agonists and Beta-Blockers in Asthma; Unraveling a Paradox
9:50am – 10:30am	Suzanne Gaudet, Dana-Farber Cancer Institute & Harvard Medical School Variability in the Control of Ligand-Induced Cell Death
10:30am – 10:50am	Break
10:50am – 11:30am	Philippe Cluzel, Harvard University Genealogy of the Multi-Antibiotics Resistance System in Bacteria
11:30am – 12:10pm	Emily Pace. Merrimack Pharmaceuticals Therapeutically Targeting ErbB3: A Key Node in Ligand-Induced Activation of the ErbB-PI3K Axis
12:10pm – 12:50pm	Shubha Govind, City University of New York Biology of Microtumors and Inflammation: Studies in Drosophila
12:50pm – 1:40pm	Lunch
Session Two: Genomics and Proteomics
1:40pm – 2:20pm	Elba Serrano, New Mexico State University and Cell Decision Processes Center, MIT Organ Systems of the Inner Ear and Disorders of Hearing and Balance
2:20pm – 3:00pm	Stanley Shaw, MGH Center for Systems Biology Placing Disease Mutations in Context: Small Molecule-Gene Interactions in Patient Cells
3:00pm – 3:40pm	Nathanael Gray, Dana Farber Cancer Institute Pfizer-CSB² Prize Recipient Discovering and Exploiting Kinase Inhibitors to Treat Cancer
3:40pm – 4:00pm	Break
4:00pm – 4:30pm	Brian Harms, Merrimack Pharmaceuticals (Poster #26) Computational Modeling and Simulation Guide the Development of MM-111, a Bispecific Antibody Targeting ErbB3 in ErbB2-Overexpressing Tumors
4:30pm – 5:00pm	Taran Gujral, Harvard University (Poster #22) A System-Wide Analysis of the Wnt Signaling Network Identifies Novel Markers of Tumor Progression
5:00pm – 5:30pm	Lightning Talks: Poster Overviews from Selected Presenters
5:30pm – 7:00pm	Poster Session & Refreshments
7:00pm	Adjourn

Friday, June 19, 2009

7:45am – 8:30am	Continental Breakfast & Registration
Session Three: Systems Pharmacology
8:30am – 9:10am	A.J. Marian Walhout, University of Massachusetts Medical School Gene-Centered Regulatory Networks
9:10am – 9:50am	Gabriel Helmlinger, Novartis Institutes for Biomedical Research Drug-Disease Modeling and its Applications in Model-Based Pharmaceutical R&D
9:50am – 10:30am	Olga Troyanskaya, Princeton University Understanding Human Disease Through Functional Networks
10:30am – 10:50am	Break
10:50am – 11:30am	Vamsi K. Mootha, Harvard Medical School Defining the Genomic Basis and Metabolic Consequences of Human Mitochondrial Disorders
11:30am – 12:10pm	Uri Alon, Weizmann Institute Dynamic Proteomics of Cancer Cells Responding to Drugs
12:10pm – 12:50pm	Ernest Fraenkel, Massachusetts Institute of Technology Merrimack-CSB²Prize Recipient Using High-Throughput Data to Understand Disease
12:50pm	Adjourn

Public Transportation

The MBTA website will help you navigate Boston’s excellent public transit system.

D Line (Green) Subway: Take train to Longwood Station. From station, turn left on to Chapel Street and walk up a short hill to Longwood Avenue. Turn left on to Longwood Avenue. Follow until Avenue Louis Pasteur and take left. The Conference Center is on the left (about a 10 minute walk).

E Line (Green) Subway: Take train to Longwood Medical Area Station. From stop, proceed down Longwood Avenue towards the hospitals. Take right onto Avenue Louis Pasteur. The Conference Center is located on the left (about a 2 minute walk).